<font face="arial" size="1" color="gray">
<table border="1" cellpadding="10">
<tr bgcolor="lightgray">
<th>EV_ID</th>
<th>DB_ID</th>
<th>TrialID</th>
<th>ArmA_TotalShort</th>
<th>ArmB_TotalShort</th>
<th>Outcome</th>
<th>Value</th>
<th>Direction</th>
<th>Significance</th>
<th>GRADE Result</th>
<tr>
<td>1</td>
<td>1</td>
<td>AtagiJJCO2005</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>1YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>2</td>
<td>1</td>
<td>AtagiJJCO2005</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>0.7576</td>
<td>inf</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>3</td>
<td>1</td>
<td>AtagiJJCO2005</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>4</td>
<td>1</td>
<td>AtagiJJCO2005</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>5</td>
<td>1</td>
<td>AtagiJJCO2005</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>6</td>
<td>1</td>
<td>AtagiJJCO2005</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>ToxicDeathRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>7</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>1YrRiskRatio</td>
<td>0.9155</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>8</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>2YrRiskRatio</td>
<td>0.7609</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>9</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>0.7545</td>
<td>inf</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>10</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>0.8654</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>11</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>12</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>13</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>3.0</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>14</td>
<td>2</td>
<td>AtagiLancetOnc2012</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo (daily); 60 in 30</td>
<td>ToxicDeathRiskRatio</td>
<td>1.3333</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>15</td>
<td>3</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30</td>
<td>1YrRiskRatio</td>
<td>0.9524</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>16</td>
<td>3</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30</td>
<td>2YrRiskRatio</td>
<td>0.8966</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>17</td>
<td>3</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>0.8118</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>18</td>
<td>3</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>0.8689</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>19</td>
<td>3</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.4211</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>20</td>
<td>4</td>
<td>BallRTOnc1999</td>
<td>Ind carbo; 60 in 30</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>1YrRiskRatio</td>
<td>1.0678</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>21</td>
<td>4</td>
<td>BallRTOnc1999</td>
<td>Ind carbo; 60 in 30</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>2YrRiskRatio</td>
<td>1.45</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>22</td>
<td>4</td>
<td>BallRTOnc1999</td>
<td>Ind carbo; 60 in 30</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>MedianOSRiskRatio</td>
<td>1.1333</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>23</td>
<td>4</td>
<td>BallRTOnc1999</td>
<td>Ind carbo; 60 in 30</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>ResponseRateRiskRatio</td>
<td>1.0339</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>24</td>
<td>4</td>
<td>BallRTOnc1999</td>
<td>Ind carbo; 60 in 30</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.413</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>25</td>
<td>5</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>1YrRiskRatio</td>
<td>0.9836</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>26</td>
<td>5</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>2YrRiskRatio</td>
<td>0.9286</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>27</td>
<td>5</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>MedianOSRiskRatio</td>
<td>0.9583</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>28</td>
<td>5</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>ResponseRateRiskRatio</td>
<td>0.8689</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>29</td>
<td>5</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.2857</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>30</td>
<td>6</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>1YrRiskRatio</td>
<td>1.0169</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>31</td>
<td>6</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>2YrRiskRatio</td>
<td>1.3</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>32</td>
<td>6</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>MedianOSRiskRatio</td>
<td>0.92</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>33</td>
<td>6</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>ResponseRateRiskRatio</td>
<td>0.8983</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>34</td>
<td>6</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (alone)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.1739</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>35</td>
<td>7</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30</td>
<td>1YrRiskRatio</td>
<td>0.9683</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>36</td>
<td>7</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30</td>
<td>2YrRiskRatio</td>
<td>0.9655</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>37</td>
<td>7</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>0.8471</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>38</td>
<td>7</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>39</td>
<td>7</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.4737</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>40</td>
<td>8</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>1YrRiskRatio</td>
<td>1.0339</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>41</td>
<td>8</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>2YrRiskRatio</td>
<td>1.4</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>42</td>
<td>8</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>MedianOSRiskRatio</td>
<td>0.96</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>43</td>
<td>8</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>ResponseRateRiskRatio</td>
<td>1.0339</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>44</td>
<td>8</td>
<td>BallRTOnc1999</td>
<td>60 in 30 (3 weeks; BD)</td>
<td>Ind carbo; 60 in 30 (3 weeks; BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.6087</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>45</td>
<td>9</td>
<td>BlankeJCO1995</td>
<td>60 in 30 (alone)</td>
<td>Conc cis; 60 in 30</td>
<td>1YrRiskRatio</td>
<td>1.0465</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>46</td>
<td>9</td>
<td>BlankeJCO1995</td>
<td>60 in 30 (alone)</td>
<td>Conc cis; 60 in 30</td>
<td>2YrRiskRatio</td>
<td>0.7222</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>47</td>
<td>9</td>
<td>BlankeJCO1995</td>
<td>60 in 30 (alone)</td>
<td>Conc cis; 60 in 30</td>
<td>5YrRiskRatio</td>
<td>0.4</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>48</td>
<td>9</td>
<td>BlankeJCO1995</td>
<td>60 in 30 (alone)</td>
<td>Conc cis; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.0707</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>49</td>
<td>9</td>
<td>BlankeJCO1995</td>
<td>60 in 30 (alone)</td>
<td>Conc cis; 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>0.76</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>50</td>
<td>9</td>
<td>BlankeJCO1995</td>
<td>60 in 30 (alone)</td>
<td>Conc cis; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>51</td>
<td>10</td>
<td>BonnerCancer1998</td>
<td>60 in 30 (alone)</td>
<td>Conc cis-etop; 60 in 40 (BD; split)</td>
<td>1YrRiskRatio</td>
<td>0.6</td>
<td>inf</td>
<td>not_sig</td>
<td>Very low</td>
</tr>
<tr>
<td>52</td>
<td>10</td>
<td>BonnerCancer1998</td>
<td>60 in 30 (alone)</td>
<td>Conc cis-etop; 60 in 40 (BD; split)</td>
<td>ResponseRateRiskRatio</td>
<td>0.9268</td>
<td>inf</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>53</td>
<td>10</td>
<td>BonnerCancer1998</td>
<td>60 in 30 (alone)</td>
<td>Conc cis-etop; 60 in 40 (BD; split)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.75</td>
<td>sup</td>
<td>not_sig</td>
<td>Very low</td>
</tr>
<tr>
<td>54</td>
<td>11</td>
<td>BonnerCancer1998</td>
<td>60 in 30 (alone)</td>
<td>60 in 40 (BD; split; alone)</td>
<td>1YrRiskRatio</td>
<td>0.6</td>
<td>inf</td>
<td>not_sig</td>
<td>Very low</td>
</tr>
<tr>
<td>55</td>
<td>11</td>
<td>BonnerCancer1998</td>
<td>60 in 30 (alone)</td>
<td>60 in 40 (BD; split; alone)</td>
<td>ResponseRateRiskRatio</td>
<td>0.5938</td>
<td>inf</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>56</td>
<td>11</td>
<td>BonnerCancer1998</td>
<td>60 in 30 (alone)</td>
<td>60 in 40 (BD; split; alone)</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Very low</td>
</tr>
<tr>
<td>57</td>
<td>12</td>
<td>BonnerCancer1998</td>
<td>60 in 40 (BD; split; alone)</td>
<td>Conc cis-etop; 60 in 40 (BD; split)</td>
<td>1YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Very low</td>
</tr>
<tr>
<td>58</td>
<td>12</td>
<td>BonnerCancer1998</td>
<td>60 in 40 (BD; split; alone)</td>
<td>Conc cis-etop; 60 in 40 (BD; split)</td>
<td>ResponseRateRiskRatio</td>
<td>1.561</td>
<td>sup</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>59</td>
<td>12</td>
<td>BonnerCancer1998</td>
<td>60 in 40 (BD; split; alone)</td>
<td>Conc cis-etop; 60 in 40 (BD; split)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.75</td>
<td>sup</td>
<td>not_sig</td>
<td>Very low</td>
</tr>
<tr>
<td>60</td>
<td>13</td>
<td>CakirLungCa2004</td>
<td>64 in 32 (alone)</td>
<td>Conc cis; 64 in 32</td>
<td>3YrRiskRatio</td>
<td>0.2</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>61</td>
<td>13</td>
<td>CakirLungCa2004</td>
<td>64 in 32 (alone)</td>
<td>Conc cis; 64 in 32</td>
<td>ResponseRateRiskRatio</td>
<td>0.6923</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>62</td>
<td>13</td>
<td>CakirLungCa2004</td>
<td>64 in 32 (alone)</td>
<td>Conc cis; 64 in 32</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.7647</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>63</td>
<td>13</td>
<td>CakirLungCa2004</td>
<td>64 in 32 (alone)</td>
<td>Conc cis; 64 in 32</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.8182</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>64</td>
<td>13</td>
<td>CakirLungCa2004</td>
<td>64 in 32 (alone)</td>
<td>Conc cis; 64 in 32</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.9815</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>65</td>
<td>14</td>
<td>CarterClinLungCa2012</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30; Cons paclitaxel</td>
<td>1YrRiskRatio</td>
<td>0.8571</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>66</td>
<td>14</td>
<td>CarterClinLungCa2012</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30; Cons paclitaxel</td>
<td>2YrRiskRatio</td>
<td>0.7241</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>67</td>
<td>14</td>
<td>CarterClinLungCa2012</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30; Cons paclitaxel</td>
<td>3YrRiskRatio</td>
<td>0.6579</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>68</td>
<td>14</td>
<td>CarterClinLungCa2012</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30; Cons paclitaxel</td>
<td>MedianOSRiskRatio</td>
<td>0.5985</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>69</td>
<td>14</td>
<td>CarterClinLungCa2012</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30; Cons paclitaxel</td>
<td>ResponseRateRiskRatio</td>
<td>1.2373</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>70</td>
<td>14</td>
<td>CarterClinLungCa2012</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30; Cons paclitaxel</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>2.0</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>71</td>
<td>14</td>
<td>CarterClinLungCa2012</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel (B); 60 in 30; Cons paclitaxel</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>72</td>
<td>15</td>
<td>ClamonJCO1999</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Ind cis-vinB; Conc carbo; 60 in 30</td>
<td>1YrRiskRatio</td>
<td>0.9643</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>73</td>
<td>15</td>
<td>ClamonJCO1999</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Ind cis-vinB; Conc carbo; 60 in 30</td>
<td>2YrRiskRatio</td>
<td>0.8966</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>74</td>
<td>15</td>
<td>ClamonJCO1999</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Ind cis-vinB; Conc carbo; 60 in 30</td>
<td>3YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>75</td>
<td>15</td>
<td>ClamonJCO1999</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Ind cis-vinB; Conc carbo; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.0075</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>76</td>
<td>15</td>
<td>ClamonJCO1999</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Ind cis-vinB; Conc carbo; 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.16</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>77</td>
<td>15</td>
<td>ClamonJCO1999</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Ind cis-vinB; Conc carbo; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.3333</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>78</td>
<td>15</td>
<td>ClamonJCO1999</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Ind cis-vinB; Conc carbo; 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>5.0</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>79</td>
<td>16</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>5YrRiskRatio</td>
<td>0.625</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>80</td>
<td>16</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>MedianOSRiskRatio</td>
<td>0.8588</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>81</td>
<td>16</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>ResponseRateRiskRatio</td>
<td>0.8714</td>
<td>inf</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>82</td>
<td>16</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.9506</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>83</td>
<td>16</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.1818</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>84</td>
<td>16</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>85</td>
<td>17</td>
<td>CurranJNCI2011</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>5YrRiskRatio</td>
<td>1.2308</td>
<td>sup</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>86</td>
<td>17</td>
<td>CurranJNCI2011</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>MedianOSRiskRatio</td>
<td>1.0897</td>
<td>sup</td>
<td>sig</td>
<td>Good</td>
</tr>
<tr>
<td>87</td>
<td>17</td>
<td>CurranJNCI2011</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>ResponseRateRiskRatio</td>
<td>1.0769</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>88</td>
<td>17</td>
<td>CurranJNCI2011</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.5283</td>
<td>inf</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>89</td>
<td>17</td>
<td>CurranJNCI2011</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.4889</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>90</td>
<td>17</td>
<td>CurranJNCI2011</td>
<td>Conc cis-vinB; 60 in 30 (A)</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.9375</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>91</td>
<td>18</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>5YrRiskRatio</td>
<td>0.7692</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>92</td>
<td>18</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>MedianOSRiskRatio</td>
<td>0.9359</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>93</td>
<td>18</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>ResponseRateRiskRatio</td>
<td>0.9385</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>94</td>
<td>18</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.4528</td>
<td>inf</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>95</td>
<td>18</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.0889</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>96</td>
<td>18</td>
<td>CurranJNCI2011</td>
<td>Ind cis-vinB; 60 in 30</td>
<td>Conc cis-etop; 69.6 in 58 (BD)</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.9375</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>97</td>
<td>19</td>
<td>FournelJCO2005</td>
<td>Ind cis-vin (A); 66 in 33</td>
<td>Conc cis-etop; 66 in 33; Cons cis-vin</td>
<td>1YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>98</td>
<td>19</td>
<td>FournelJCO2005</td>
<td>Ind cis-vin (A); 66 in 33</td>
<td>Conc cis-etop; 66 in 33; Cons cis-vin</td>
<td>2YrRiskRatio</td>
<td>0.6923</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>99</td>
<td>19</td>
<td>FournelJCO2005</td>
<td>Ind cis-vin (A); 66 in 33</td>
<td>Conc cis-etop; 66 in 33; Cons cis-vin</td>
<td>MedianOSRiskRatio</td>
<td>0.8896</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>100</td>
<td>19</td>
<td>FournelJCO2005</td>
<td>Ind cis-vin (A); 66 in 33</td>
<td>Conc cis-etop; 66 in 33; Cons cis-vin</td>
<td>ResponseRateRiskRatio</td>
<td>1.102</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>101</td>
<td>19</td>
<td>FournelJCO2005</td>
<td>Ind cis-vin (A); 66 in 33</td>
<td>Conc cis-etop; 66 in 33; Cons cis-vin</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.1429</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>102</td>
<td>19</td>
<td>FournelJCO2005</td>
<td>Ind cis-vin (A); 66 in 33</td>
<td>Conc cis-etop; 66 in 33; Cons cis-vin</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.1</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>103</td>
<td>19</td>
<td>FournelJCO2005</td>
<td>Ind cis-vin (A); 66 in 33</td>
<td>Conc cis-etop; 66 in 33; Cons cis-vin</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>2.2</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>104</td>
<td>20</td>
<td>GoudaJENCI2006</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>2YrRiskRatio</td>
<td>1.8</td>
<td>sup</td>
<td>sig</td>
<td>Low</td>
</tr>
<tr>
<td>105</td>
<td>20</td>
<td>GoudaJENCI2006</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>ResponseRateRiskRatio</td>
<td>1.975</td>
<td>sup</td>
<td>sig</td>
<td>Low</td>
</tr>
<tr>
<td>106</td>
<td>20</td>
<td>GoudaJENCI2006</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>5.0</td>
<td>inf</td>
<td>null</td>
<td>Low</td>
</tr>
<tr>
<td>107</td>
<td>20</td>
<td>GoudaJENCI2006</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>Grd3OesToxRiskRatio</td>
<td>5.0</td>
<td>inf</td>
<td>null</td>
<td>Low</td>
</tr>
<tr>
<td>108</td>
<td>21</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>2YrRiskRatio</td>
<td>0.8889</td>
<td>inf</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>109</td>
<td>21</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>0.9747</td>
<td>inf</td>
<td>not_sig</td>
<td>Low</td>
</tr>
<tr>
<td>110</td>
<td>21</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.2</td>
<td>inf</td>
<td>null</td>
<td>Low</td>
</tr>
<tr>
<td>111</td>
<td>21</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.2</td>
<td>inf</td>
<td>null</td>
<td>Low</td>
</tr>
<tr>
<td>112</td>
<td>22</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>2YrRiskRatio</td>
<td>1.6</td>
<td>sup</td>
<td>sig</td>
<td>Low</td>
</tr>
<tr>
<td>113</td>
<td>22</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>ResponseRateRiskRatio</td>
<td>1.925</td>
<td>sup</td>
<td>sig</td>
<td>Low</td>
</tr>
<tr>
<td>114</td>
<td>22</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>6.0</td>
<td>inf</td>
<td>null</td>
<td>Low</td>
</tr>
<tr>
<td>115</td>
<td>22</td>
<td>GoudaJENCI2006</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 60 in 30</td>
<td>60 in 30 (alone)</td>
<td>Grd3OesToxRiskRatio</td>
<td>6.0</td>
<td>inf</td>
<td>null</td>
<td>Low</td>
</tr>
<tr>
<td>116</td>
<td>23</td>
<td>GroenAnnOnc2004</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo; 60 in 30</td>
<td>2YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Poor</td>
</tr>
<tr>
<td>117</td>
<td>23</td>
<td>GroenAnnOnc2004</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>0.9915</td>
<td>inf</td>
<td>not_sig</td>
<td>Poor</td>
</tr>
<tr>
<td>118</td>
<td>23</td>
<td>GroenAnnOnc2004</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo; 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>1.2432</td>
<td>sup</td>
<td>not_sig</td>
<td>Poor</td>
</tr>
<tr>
<td>119</td>
<td>23</td>
<td>GroenAnnOnc2004</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo; 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>120</td>
<td>23</td>
<td>GroenAnnOnc2004</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.2222</td>
<td>sup</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>121</td>
<td>23</td>
<td>GroenAnnOnc2004</td>
<td>60 in 30 (alone)</td>
<td>Conc carbo; 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>2.0</td>
<td>inf</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>122</td>
<td>24</td>
<td>HuberJCO2006</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Ind carbo-paclitaxel; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.3357</td>
<td>sup</td>
<td>not_sig</td>
<td>Poor</td>
</tr>
<tr>
<td>123</td>
<td>24</td>
<td>HuberJCO2006</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Ind carbo-paclitaxel; 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>124</td>
<td>24</td>
<td>HuberJCO2006</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Ind carbo-paclitaxel; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.5</td>
<td>sup</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>125</td>
<td>24</td>
<td>HuberJCO2006</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Ind carbo-paclitaxel; 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>126</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>1YrRiskRatio</td>
<td>1.46</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>127</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>2YrRiskRatio</td>
<td>1.2963</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>128</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>3YrRiskRatio</td>
<td>1.4375</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>129</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>5YrRiskRatio</td>
<td>1.3125</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>130</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>MedianOSRiskRatio</td>
<td>1.3846</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>131</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>ResponseRateRiskRatio</td>
<td>1.1935</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>132</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.5</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>133</td>
<td>25</td>
<td>JeremicJCO1995</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.8571</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>134</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>1YrRiskRatio</td>
<td>0.5342</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>135</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>2YrRiskRatio</td>
<td>0.7143</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>136</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>3YrRiskRatio</td>
<td>0.2609</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>137</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>5YrRiskRatio</td>
<td>0.2333</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>138</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>MedianOSRiskRatio</td>
<td>0.4444</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>139</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>ResponseRateRiskRatio</td>
<td>0.8514</td>
<td>inf</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>140</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>141</td>
<td>26</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (A); 64.8 in 54 (BD)</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>142</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>1YrRiskRatio</td>
<td>0.78</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>143</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>2YrRiskRatio</td>
<td>0.9259</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>144</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>3YrRiskRatio</td>
<td>0.375</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>145</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>5YrRiskRatio</td>
<td>0.3063</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>146</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>MedianOSRiskRatio</td>
<td>0.6154</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>147</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>ResponseRateRiskRatio</td>
<td>1.0161</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>148</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>149</td>
<td>27</td>
<td>JeremicJCO1995</td>
<td>64.8 in 54 (BD, alone)</td>
<td>Conc carbo-etop (B);  64.8 in 54 (BD)</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>150</td>
<td>28</td>
<td>JeremicJCO1996</td>
<td>69.6 in 58 (BD; alone)</td>
<td>Conc carbo-etop; 69.6 in 58 (BD)</td>
<td>1YrRiskRatio</td>
<td>0.9189</td>
<td>inf</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>151</td>
<td>28</td>
<td>JeremicJCO1996</td>
<td>69.6 in 58 (BD; alone)</td>
<td>Conc carbo-etop; 69.6 in 58 (BD)</td>
<td>2YrRiskRatio</td>
<td>0.6047</td>
<td>inf</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>152</td>
<td>28</td>
<td>JeremicJCO1996</td>
<td>69.6 in 58 (BD; alone)</td>
<td>Conc carbo-etop; 69.6 in 58 (BD)</td>
<td>3YrRiskRatio</td>
<td>0.4783</td>
<td>inf</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>153</td>
<td>28</td>
<td>JeremicJCO1996</td>
<td>69.6 in 58 (BD; alone)</td>
<td>Conc carbo-etop; 69.6 in 58 (BD)</td>
<td>MedianOSRiskRatio</td>
<td>0.6364</td>
<td>inf</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>154</td>
<td>28</td>
<td>JeremicJCO1996</td>
<td>69.6 in 58 (BD; alone)</td>
<td>Conc carbo-etop; 69.6 in 58 (BD)</td>
<td>ResponseRateRiskRatio</td>
<td>0.913</td>
<td>inf</td>
<td>not_sig</td>
<td>Very low</td>
</tr>
<tr>
<td>155</td>
<td>28</td>
<td>JeremicJCO1996</td>
<td>69.6 in 58 (BD; alone)</td>
<td>Conc carbo-etop; 69.6 in 58 (BD)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.75</td>
<td>sup</td>
<td>sig</td>
<td>Very low</td>
</tr>
<tr>
<td>156</td>
<td>29</td>
<td>LandgrenCancer1974</td>
<td>60 in 20 (split; alone)</td>
<td>Conc hydroxyurea; 60 in 20 (split)</td>
<td>1YrRiskRatio</td>
<td>1.0435</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>157</td>
<td>29</td>
<td>LandgrenCancer1974</td>
<td>60 in 20 (split; alone)</td>
<td>Conc hydroxyurea; 60 in 20 (split)</td>
<td>2YrRiskRatio</td>
<td>1.0909</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>158</td>
<td>29</td>
<td>LandgrenCancer1974</td>
<td>60 in 20 (split; alone)</td>
<td>Conc hydroxyurea; 60 in 20 (split)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.75</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>159</td>
<td>30</td>
<td>LuCJLC2005</td>
<td>Conc cis-vinB; 60 in 30 (B)</td>
<td>60 in 30 (alone)</td>
<td>1YrRiskRatio</td>
<td>1.2453</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>160</td>
<td>30</td>
<td>LuCJLC2005</td>
<td>Conc cis-vinB; 60 in 30 (B)</td>
<td>60 in 30 (alone)</td>
<td>2YrRiskRatio</td>
<td>1.303</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>161</td>
<td>30</td>
<td>LuCJLC2005</td>
<td>Conc cis-vinB; 60 in 30 (B)</td>
<td>60 in 30 (alone)</td>
<td>ResponseRateRiskRatio</td>
<td>1.1765</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>162</td>
<td>30</td>
<td>LuCJLC2005</td>
<td>Conc cis-vinB; 60 in 30 (B)</td>
<td>60 in 30 (alone)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>100000000.0</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>163</td>
<td>30</td>
<td>LuCJLC2005</td>
<td>Conc cis-vinB; 60 in 30 (B)</td>
<td>60 in 30 (alone)</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.3125</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>164</td>
<td>31</td>
<td>MaguireJCO2011</td>
<td>Ind cis-vin (B); 55 in 20</td>
<td>Conc cis-vin (B); 55 in 20</td>
<td>2YrRiskRatio</td>
<td>0.7778</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>165</td>
<td>31</td>
<td>MaguireJCO2011</td>
<td>Ind cis-vin (B); 55 in 20</td>
<td>Conc cis-vin (B); 55 in 20</td>
<td>3YrRiskRatio</td>
<td>0.7105</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>166</td>
<td>31</td>
<td>MaguireJCO2011</td>
<td>Ind cis-vin (B); 55 in 20</td>
<td>Conc cis-vin (B); 55 in 20</td>
<td>MedianOSRiskRatio</td>
<td>0.6889</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>167</td>
<td>31</td>
<td>MaguireJCO2011</td>
<td>Ind cis-vin (B); 55 in 20</td>
<td>Conc cis-vin (B); 55 in 20</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.2222</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>168</td>
<td>31</td>
<td>MaguireJCO2011</td>
<td>Ind cis-vin (B); 55 in 20</td>
<td>Conc cis-vin (B); 55 in 20</td>
<td>ToxicDeathRiskRatio</td>
<td>0.6667</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>169</td>
<td>32</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>1YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>170</td>
<td>32</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>5YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>171</td>
<td>32</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>0.8592</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>172</td>
<td>32</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>173</td>
<td>32</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>174</td>
<td>33</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>1YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>175</td>
<td>33</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>5YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>176</td>
<td>33</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>177</td>
<td>33</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>178</td>
<td>33</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel (daily); 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>179</td>
<td>34</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>1YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>180</td>
<td>34</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>5YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>181</td>
<td>34</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>0.8592</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>182</td>
<td>34</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>183</td>
<td>34</td>
<td>NymanLungCa2009</td>
<td>Ind carbo-paclitaxel; Conc carbo-paclitaxel; 64.6 in 38 (continuous)</td>
<td>Ind carbo-paclitaxel; Conc paclitaxel; 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>184</td>
<td>35</td>
<td>ReinfussNowotory2005</td>
<td>Ind cis-vin; 70.2 in 39</td>
<td>Conc cis-vin; 70.2 in 39</td>
<td>2YrRiskRatio</td>
<td>1.04</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>185</td>
<td>35</td>
<td>ReinfussNowotory2005</td>
<td>Ind cis-vin; 70.2 in 39</td>
<td>Conc cis-vin; 70.2 in 39</td>
<td>ResponseRateRiskRatio</td>
<td>0.9853</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>186</td>
<td>36</td>
<td>ScagliottiBJC2006</td>
<td>Ind cis-docetaxel; Conc docetaxel; 60 in 30</td>
<td>Ind cis-docetaxel; 60 in 30</td>
<td>1YrRiskRatio</td>
<td>0.9492</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>187</td>
<td>36</td>
<td>ScagliottiBJC2006</td>
<td>Ind cis-docetaxel; Conc docetaxel; 60 in 30</td>
<td>Ind cis-docetaxel; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.0643</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>188</td>
<td>36</td>
<td>ScagliottiBJC2006</td>
<td>Ind cis-docetaxel; Conc docetaxel; 60 in 30</td>
<td>Ind cis-docetaxel; 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>1.2083</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>189</td>
<td>36</td>
<td>ScagliottiBJC2006</td>
<td>Ind cis-docetaxel; Conc docetaxel; 60 in 30</td>
<td>Ind cis-docetaxel; 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>190</td>
<td>36</td>
<td>ScagliottiBJC2006</td>
<td>Ind cis-docetaxel; Conc docetaxel; 60 in 30</td>
<td>Ind cis-docetaxel; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>100000000.0</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>191</td>
<td>37</td>
<td>Schaake-KoningNEJM1992</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>1YrRiskRatio</td>
<td>0.8148</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>192</td>
<td>37</td>
<td>Schaake-KoningNEJM1992</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>2YrRiskRatio</td>
<td>0.7308</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>193</td>
<td>37</td>
<td>Schaake-KoningNEJM1992</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>3YrRiskRatio</td>
<td>0.8125</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>194</td>
<td>37</td>
<td>Schaake-KoningNEJM1992</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>ResponseRateRiskRatio</td>
<td>0.9091</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>195</td>
<td>37</td>
<td>Schaake-KoningNEJM1992</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.3333</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>196</td>
<td>37</td>
<td>Schaake-KoningNEJM1992</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.2</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>197</td>
<td>38</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>1YrRiskRatio</td>
<td>1.0455</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>198</td>
<td>38</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>2YrRiskRatio</td>
<td>0.6842</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>199</td>
<td>38</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>3YrRiskRatio</td>
<td>0.1538</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>200</td>
<td>38</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>ResponseRateRiskRatio</td>
<td>0.95</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>201</td>
<td>38</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>202</td>
<td>38</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis; 55 in 20 (split)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>203</td>
<td>39</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>1YrRiskRatio</td>
<td>0.8519</td>
<td>inf</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>204</td>
<td>39</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>2YrRiskRatio</td>
<td>0.5</td>
<td>inf</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>205</td>
<td>39</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>3YrRiskRatio</td>
<td>0.125</td>
<td>inf</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>206</td>
<td>39</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>ResponseRateRiskRatio</td>
<td>0.8636</td>
<td>inf</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>207</td>
<td>39</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>208</td>
<td>39</td>
<td>Schaake-KoningNEJM1992</td>
<td>55 in 20 (split; alone)</td>
<td>Conc cis (daily); 55 in 20 (split)</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.0</td>
<td>sup</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>209</td>
<td>40</td>
<td>SegawaJCO2010</td>
<td>Conc cis-docetaxel; 60 in 30</td>
<td>Conc cis-MMC-VinD; 60 in 30</td>
<td>2YrRiskRatio</td>
<td>1.25</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>210</td>
<td>40</td>
<td>SegawaJCO2010</td>
<td>Conc cis-docetaxel; 60 in 30</td>
<td>Conc cis-MMC-VinD; 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.1308</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>211</td>
<td>40</td>
<td>SegawaJCO2010</td>
<td>Conc cis-docetaxel; 60 in 30</td>
<td>Conc cis-MMC-VinD; 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>1.0986</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>212</td>
<td>40</td>
<td>SegawaJCO2010</td>
<td>Conc cis-docetaxel; 60 in 30</td>
<td>Conc cis-MMC-VinD; 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.6489</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>213</td>
<td>40</td>
<td>SegawaJCO2010</td>
<td>Conc cis-docetaxel; 60 in 30</td>
<td>Conc cis-MMC-VinD; 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>2.3333</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>214</td>
<td>40</td>
<td>SegawaJCO2010</td>
<td>Conc cis-docetaxel; 60 in 30</td>
<td>Conc cis-MMC-VinD; 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.4286</td>
<td>inf</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>215</td>
<td>41</td>
<td>TrovoRedJ1992</td>
<td>45 in 15 (alone)</td>
<td>Conc cis (daily); 45 in 15</td>
<td>MedianOSRiskRatio</td>
<td>1.0331</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>216</td>
<td>41</td>
<td>TrovoRedJ1992</td>
<td>45 in 15 (alone)</td>
<td>Conc cis (daily); 45 in 15</td>
<td>ResponseRateRiskRatio</td>
<td>1.164</td>
<td>sup</td>
<td>not_sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>217</td>
<td>41</td>
<td>TrovoRedJ1992</td>
<td>45 in 15 (alone)</td>
<td>Conc cis (daily); 45 in 15</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>0.6585</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>218</td>
<td>41</td>
<td>TrovoRedJ1992</td>
<td>45 in 15 (alone)</td>
<td>Conc cis (daily); 45 in 15</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.5</td>
<td>sup</td>
<td>null</td>
<td>Moderate</td>
</tr>
<tr>
<td>219</td>
<td>42</td>
<td>WuCJLC2006</td>
<td>Conc cis-vin (D); 60 in 30</td>
<td>60 in 30; Cons cis-vin (E)</td>
<td>ResponseRateRiskRatio</td>
<td>1.3793</td>
<td>sup</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>220</td>
<td>42</td>
<td>WuCJLC2006</td>
<td>Conc cis-vin (D); 60 in 30</td>
<td>60 in 30; Cons cis-vin (E)</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.5294</td>
<td>inf</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>221</td>
<td>42</td>
<td>WuCJLC2006</td>
<td>Conc cis-vin (D); 60 in 30</td>
<td>60 in 30; Cons cis-vin (E)</td>
<td>Grd3OesToxRiskRatio</td>
<td>1.9</td>
<td>inf</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>222</td>
<td>42</td>
<td>WuCJLC2006</td>
<td>Conc cis-vin (D); 60 in 30</td>
<td>60 in 30; Cons cis-vin (E)</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.625</td>
<td>inf</td>
<td>null</td>
<td>Poor</td>
</tr>
<tr>
<td>223</td>
<td>43</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>3YrRiskRatio</td>
<td>1.4583</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>224</td>
<td>43</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>5YrRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>225</td>
<td>43</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.0354</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>226</td>
<td>43</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>1.1964</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>227</td>
<td>43</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.5574</td>
<td>inf</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>228</td>
<td>43</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>2.0</td>
<td>inf</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>229</td>
<td>43</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.25</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>230</td>
<td>44</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>3YrRiskRatio</td>
<td>1.3462</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>231</td>
<td>44</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>5YrRiskRatio</td>
<td>0.9474</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>232</td>
<td>44</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>MedianOSRiskRatio</td>
<td>0.9318</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>233</td>
<td>44</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>ResponseRateRiskRatio</td>
<td>1.0635</td>
<td>sup</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>234</td>
<td>44</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.5574</td>
<td>inf</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>235</td>
<td>44</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.75</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>236</td>
<td>44</td>
<td>YamamotoJCO2010</td>
<td>Conc cis-MMC-VinD; 60 in 30; Cons cis-MMC-VinD</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>0.25</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>237</td>
<td>45</td>
<td>YamamotoJCO2010</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>3YrRiskRatio</td>
<td>0.0091</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>238</td>
<td>45</td>
<td>YamamotoJCO2010</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>5YrRiskRatio</td>
<td>0.9474</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>239</td>
<td>45</td>
<td>YamamotoJCO2010</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>MedianOSRiskRatio</td>
<td>0.9</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>240</td>
<td>45</td>
<td>YamamotoJCO2010</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>ResponseRateRiskRatio</td>
<td>0.8889</td>
<td>inf</td>
<td>not_sig</td>
<td>Good</td>
</tr>
<tr>
<td>241</td>
<td>45</td>
<td>YamamotoJCO2010</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>242</td>
<td>45</td>
<td>YamamotoJCO2010</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>Grd3OesToxRiskRatio</td>
<td>0.375</td>
<td>sup</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>243</td>
<td>45</td>
<td>YamamotoJCO2010</td>
<td>Conc carbo-iri (weekly); 60 in 30</td>
<td>Conc carbo-paclitaxel; 60 in 30; Cons carbo-taxol</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>1.0</td>
<td>eq</td>
<td>null</td>
<td>Good</td>
</tr>
<tr>
<td>244</td>
<td>46</td>
<td>ZatloukalLungCa2004</td>
<td>Conc cis-vin (C); 60 in 30</td>
<td>Ind cis-vin (C); 60 in 30</td>
<td>1YrRiskRatio</td>
<td>130.566</td>
<td>sup</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>245</td>
<td>46</td>
<td>ZatloukalLungCa2004</td>
<td>Conc cis-vin (C); 60 in 30</td>
<td>Ind cis-vin (C); 60 in 30</td>
<td>2YrRiskRatio</td>
<td>2.3916</td>
<td>sup</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>246</td>
<td>46</td>
<td>ZatloukalLungCa2004</td>
<td>Conc cis-vin (C); 60 in 30</td>
<td>Ind cis-vin (C); 60 in 30</td>
<td>MedianOSRiskRatio</td>
<td>1.2868</td>
<td>sup</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>247</td>
<td>46</td>
<td>ZatloukalLungCa2004</td>
<td>Conc cis-vin (C); 60 in 30</td>
<td>Ind cis-vin (C); 60 in 30</td>
<td>ResponseRateRiskRatio</td>
<td>1.7021</td>
<td>sup</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>248</td>
<td>46</td>
<td>ZatloukalLungCa2004</td>
<td>Conc cis-vin (C); 60 in 30</td>
<td>Ind cis-vin (C); 60 in 30</td>
<td>Grd3NeutropeniaRiskRatio</td>
<td>1.625</td>
<td>inf</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>249</td>
<td>46</td>
<td>ZatloukalLungCa2004</td>
<td>Conc cis-vin (C); 60 in 30</td>
<td>Ind cis-vin (C); 60 in 30</td>
<td>Grd3OesToxRiskRatio</td>
<td>4.5</td>
<td>inf</td>
<td>sig</td>
<td>Moderate</td>
</tr>
<tr>
<td>250</td>
<td>46</td>
<td>ZatloukalLungCa2004</td>
<td>Conc cis-vin (C); 60 in 30</td>
<td>Ind cis-vin (C); 60 in 30</td>
<td>Grd3PneumoToxRiskRatio</td>
<td>2.0</td>
<td>inf</td>
<td>sig</td>
<td>Moderate</td>
</tr>
</table>
